Research

We’ve curated this page to provide an overview of BAGOS including a video followed by recommended research articles.

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Intro to SYT1: Baker-Gordon Syndrome

This video is an introduction to what SYT1 is and what it does, how is SYT1 affected in BAGOS and why does this happen. The video was created for the BAGOS Foundation by the MRC Cognition and Brain Sciences Unit at the University of Cambridge.

Recommended Published Research

The articles below are separated in 2 sections; Clinical and Behavioral Features and Function of SYT1 in Synapse.

Clinical and Behavioural Features

Featured

Identification of a human synaptotagmin-1 mutation that perturbs synaptic vesicle cycling

Identification of a human synaptotagmin-1 mutation that perturbs synaptic vesicle cycling

SYT1-associated neurodevelopmental disorder: a case series

SYT1-associated neurodevelopmental disorder: a case series

The neurodevelopmental spectrum of synaptic vesicle cycling disorders

The neurodevelopmental spectrum of synaptic vesicle cycling disorders

Expanding the genotype and phenotype spectrum of SYT1-associated neurodevelopmental disorder

Expanding the genotype and phenotype spectrum of SYT1-associated neurodevelopmental disorder

Function of SYT1 in Synapse

Featured

Presynaptic dysfunction in neurodevelopmental disorders: Insights from the synaptic vesicle life cycle

Presynaptic dysfunction in neurodevelopmental disorders: Insights from the synaptic vesicle life cycle

Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder

Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder

Deconstructing Synaptotagmin-1's Distinct Roles in Synaptic Vesicle Priming and Neurotransmitter Release

Deconstructing Synaptotagmin-1's Distinct Roles in Synaptic Vesicle Priming and Neurotransmitter Release

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